CAS Number: 163265-32-5 Molecular Weight: 1041.62 Salt Form: TFA Purity: >95% Sequence (3-letter): Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Nle-OH Sequence (1-letter): GSNKGAIIGL(Nle)-OH Storage: -20 °C or below
Met35 has been replaced by Nle in this Beta Amyloid fragment. Met35 is necessary for the toxicity of full length Beta Amyloid (1-40) & (1-42) to cultured hippocampal neurons. Replacement by Nle renders these peptides non-toxic.