當(dāng)前位置 ： avanti polar lipids >>> avanti polar lipids/Facade?-EM: Two Dimensional Amphiphile/1g/850522P-1g
avanti polar lipids/Facade?-EM: Two Dimensional Amphiphile/1g/850522P-1g
  • avanti polar lipids/Facade?-EM: Two Dimensional Amphiphile/1g/850522P-1g

avanti polar lipids/Facade?-EM: Two Dimensional Amphiphile/1g/850522P-1g

價(jià)格: ￥40215.00 市場價(jià): 53638.20
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請仔細(xì)核對信息。
下單后請及時(shí)聯(lián)系客服核對商品價(jià)格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費(fèi)服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價(jià)
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題

    • 850522 | Facade?-EM: Two Dimensional Amphiphile

      3α-hydroxy-7α,12α-di-((O-ß-D-maltosyl)-2-hydroxyethoxy)-cholane

      Facade?-EM: Two Dimensional Amphiphile
      Info

      Facade?-EM: Two Dimensional Amphiphile

      3α-hydroxy-7α,12α-di-((O-ß-D-maltosyl)-2-hydroxyethoxy)-cholane

      Facade?-EM: Order the Latest Two-Dimensional Amphiphile

      Facade?-EM (3α-hydroxy-7α,12α-di-((O-?-D-maltosyl)-2-hydroxyethoxy)-cholane) is a two-dimensional amphiphile with hydrophobic and hydrophilic faces. With its divergence from the traditional one-dimensional polar-head/nonpolar-tail molecules, this new class of detergents has a superior ability to stabilize integral membrane proteins. Keep reading to learn more.

      How Do Detergents Relate to Protein Research?

      One of the main challenges in protein biochemistry is the study of membrane proteins. This is especially true when working outside of the parameters of the natural lipid environment. When conducting in vitro studies, researchers rely heavily on the solubilization of membrane proteins—which typically requires wisely-chosen solubilizing detergents and mixed lipid/detergent systems.

      The Application of Facade?EM

      Facade?EM (3α-hydroxy-7α,12α-di-((O-β-D-maltosyl)-2-hydroxyethoxy)-cholane) may be used in several ways.

      It can be used as a facial amphiphile detergent to purify protoxin-II (ProTx2)-voltage-sensor domain II (VSD2)-voltage-gated sodium (NavAb) channel. It can also be used as an additive in fluorescence quenching experiments of pentaene-SM 18, or to form isotropic bicelles with p75 for nuclear magnetic resonance (NMR) studies.

      Purchase High-Quality Detergents from Avanti Polar Lipids

      From unique detergents exclusive to Avanti to detergent kits and beyond, Avanti Polar Lipids has the products, services, and expertise you need to ensure the best results from your research—every time. Order Facade?EM here, or browse our entire catalog of detergents here.

      Data
      Hygroscopic
      No
      Light Sensitive
      No
      Molecular Formula
      C52H90O25
      Percent Composition
      C 56.00%, H 8.13%, O 35.86%
      Purity
      >99%
      Stability
      1 Years
      Storage Temperature
      -20°C
      CAS Number
      1429405-95-7 CAS Registry Number is a Registered Trademark of the American Chemical Society
      FormulaWeight
      1115.256
      Exact Mass
      1114.577
      Synonyms
      FA-33α-hydroxy-7α,12α-di-((O-?-D-maltopyranosyl)ethyloxy)-cholane
      Downloads
      • ChemDraw File
      • 3D Structure
      • Structure
      • Technical Data Sheet
      • Safety Data Sheet
      References

      Xu H, Li T, Rohou A, Arthur CP, Tzakoniati F, Wong E, Estevez A, Kugel C, Franke Y, Chen J, Ciferri C, Hackos DH, Koth CM, Payandeh J. Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin. Cell. 2019 Feb 7;176(4):702-715.e14. doi: 10.1016/j.cell.2018.12.018. Epub 2019 Jan 17.

      PubMed ID: 30661758

      Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature. 2018 May;557(7704):196-201.

      PubMed ID: 29720648

      Lee, S.C., B.C. Bennett, W.X. Hong, Y. Fu, K.A. Baker, J. Marcoux, C.V. Robinson, A.B. Ward, J.R. Halpert, R.C. Stevens, C.D. Stout, M.J. Yeager, and Q. Zhang. (2013). Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proc Natl Acad Sci U S A 110:E1203-11. [PubMed]

      PubMed ID: 23479627

      Zhang, Q., X. Ma, A. Ward, W.X. Hong, V.P. Jaakola, R.C. Stevens, M.G. Finn, and G. Chang. (2007) Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl 46:7023-5. [PubMed]

      PubMed ID: 17691085

      Kot EF, Goncharuk SA, Arseniev AS, Mineev KS. Phase Transitions in Small Isotropic Bicelles. Langmuir. 2018 Mar 6. doi: 10.1021/acs.langmuir.7b03610.

      PubMed ID: 29486112
      Certificates of Analysis
      • Certificate of Analysis(Lot No. 850522P-1G-A-014and 5702PQA014)
      • Certificate of Analysis(Lot No. 850522P-200MG-A-014and 5702PNA014)
      • Certificate of Analysis(Lot No. 850522P-25MG-A-014and 5702PJA014)
      • Certificate of Analysis(Lot No. 850522P-1G-A-016and 5702PQA016)
      • Certificate of Analysis(Lot No. 850522P-25MG-A-016and 5702PJA016)
      • Certificate of Analysis(Lot No. 850522P-200MG-A-016and 5702PNA016)
      • Certificate of Analysis(Lot No. 850522P-1G-B-016and 5702PQB016)
      • Certificate of Analysis(Lot No. 850522P-200MG-A-016_5702PNA016_180924_092430and 5702PNA016)
      • Certificate of Analysis(Lot No. 850522P-1G-A-017and 5702PQA017)
      • Certificate of Analysis(Lot No. 850522P-1G-C-016and 5702PQC016)
      • Certificate of Analysis(Lot No. 850522P-25MG-A-017and 5702PJA017)
      • Certificate of Analysis(Lot No. 850522P-200MG-B-010and 5702PNB010)
      • Certificate of Analysis(Lot No. 850522P-200MG-A-018and 5702PNA018)
      • Certificate of Analysis(Lot No. 850522P-1G-A-018and 5702PQA018)
      Base Price:${originalprice|money}
      Custom Packaging:(${concentration} @$4.00/ea. + $100)${custompackagingtotal|money}
      Packaging:${concentration}
      Item Total:${totalprice|money}
      (Sales Tax may apply)
      Please select an option above.
      ${sku} - ${concentration}
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度，由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價(jià)格”為理念，直接鏈接原廠家，從全國各地原制造商嚴(yán)格挑選188款科研精品，剔除品牌溢價(jià)，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗(yàn)，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團(tuán)隊(duì)負(fù)責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴(yán)格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進(jìn)行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費(fèi)金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達(dá)！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時(shí)免費(fèi)服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯(cuò)了怎么辦？
    A：同個(gè)訂單購買多個(gè)商品可能會分為一個(gè)以上包裹發(fā)出，可能不會同時(shí)送達(dá)，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時(shí)間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個(gè)月內(nèi)（以快遞公司顯示簽收時(shí)間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請?jiān)谑盏截?4小時(shí)內(nèi)申請退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn)，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因?yàn)樯偎跃劢?，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點(diǎn)擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動(dòng)通知