Immunogen | C-terminusofratGAT-3(aa607-627)coupledtoKLH(Johnson,1996).Thissequencesisidenticaltoaminoacids607-627ofmouseGAT-4butshowsnosignificantsimilaritytomouseGAT-3. |
Epitope | C-terminus |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | GABATransporter-3(GAT-3),C-terminus.Nocross-reactivitytotheC-terminiofothertransmittertransportersdetected. |
SpeciesReactivity | |
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Gamma-aminobutyricacid(GABA)isamajorinhibitoryneurotransmitter.GABAergicneurotransmissionisterminatedbytheuptakeofGABAintothepresynapticterminalandthesurroundingastroglialcellsbysodium-dependenttransporters,suchasSLC6A11.[suppliedbyOMIM] |
GeneSymbol | |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P48066#TerminatestheactionofGABAbyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:632aminoacids;70606Da SUBCELLULARLOCATION:Membrane;Multi-passmembraneprotein. TISSUESPECIFICITY:Widespreaddistributioninthebrain. SIMILARITY:SwissProt:P48066##Belongstothesodium:neurotransmittersymporter(SNF)family. |