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Abnova/AAK1 monoclonal antibody (M02), clone 4B10/1kit/H00022848-M02
  • Abnova/AAK1 monoclonal antibody (M02), clone 4B10/1kit/H00022848-M02

Abnova/AAK1 monoclonal antibody (M02), clone 4B10/1kit/H00022848-M02

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貨號: H00022848-M02
品牌: Abnova
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      • Specification
      • Product Description:
      • Mouse monoclonal antibody raised against a partial recombinant AAK1.
      • Immunogen:
      • AAK1 (AAH02695, 315 a.a. ~ 415 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
      • Sequence:
      • LKKECPIPNVQNSPIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASV
      • Host:
      • Mouse
      • Reactivity:
      • Human
      • Isotype:
      • IgG2a Kappa
      • Quality Control Testing:
      • Antibody Reactive Against Recombinant Protein.QC Testing of H00022848-M02Western Blot detection against Immunogen (36.74 KDa) .
      • Storage Buffer:
      • In 1x PBS, pH 7.4
      • Storage Instruction:
      • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
      • MSDS:
      • PDF DownloadDownload
      • Interspecies Antigen Sequence:
      • Mouse (94); Rat (94)
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Transfected lysate)
      • Western Blot (Transfected lysate)
      • Western Blot analysis of AAK1 expression in transfected 293T cell line by AAK1 monoclonal antibody (M02), clone 4B10.Lane 1: AAK1 transfected lysate(52 KDa).Lane 2: Non-transfected lysate.
      • PDF DownloadProtocol Download
      • Western Blot (Recombinant protein)
      • PDF DownloadProtocol Download
      • Immunofluorescence
      • Immunofluorescenceenlargeenlarge this image
      • Immunofluorescence of monoclonal antibody to AAK1 on HeLa cell . [antibody concentration 10 ug/ml]
      • Sandwich ELISA (Recombinant protein)
      • Sandwich ELISA (Recombinant protein)
      • Detection limit for recombinant GST tagged AAK1 is 0.1 ng/ml as a capture antibody.
      • PDF DownloadProtocol Download
      • ELISA
      • Application Image
      • Western Blot (Transfected lysate)
      • Western Blot (Transfected lysate)
      • enlarge
      • Western Blot (Recombinant protein)
      • Immunofluorescence
      • Immunofluorescence
      • enlarge
      • Sandwich ELISA (Recombinant protein)
      • Sandwich ELISA (Recombinant protein)
      • enlarge
      • ELISA
      • Gene Information
      • Entrez GeneID:
      • 22848
      • GeneBank Accession#:
      • BC002695
      • Protein Accession#:
      • AAH02695
      • Gene Name:
      • AAK1
      • Gene Alias:
      • DKFZp686F03202,DKFZp686K16132,FLJ23712,FLJ25931,FLJ31060,FLJ42882,FLJ45252,KIAA1048,MGC138170,MGC164568,MGC164570
      • Gene Description:
      • AP2 associated kinase 1
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
      • Other Designations:
      • adaptor-associated kinase 1
      • Related Disease
      • Parkinson Disease
      • Tobacco Use Disorder
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