IL1B (Human) ELISpot Kit is a sandwich enzyme-based immunospot assay for the quantitative measurement of human IL1B.
Reactivity:
Human
Storage Instruction:
Store the kit at 4°C.
Protocol:
Protocol Download
Suitable Sample:
Cell
Sample Volume:
100 uL
Label:
Biotin-conjugated
Detection Method:
Colorimetric
Regulation Status:
For research use only (RUO)
Datasheet:
Download
Applications
Quantification
Application Image
Quantification
Gene Information
Entrez GeneID:
3553
Gene Name:
IL1B
Gene Alias:
IL-1,IL1-BETA,IL1F2
Gene Description:
interleukin 1, beta
Omim ID:
137215, 147720
Gene Ontology:
Hyperlink
Gene Summary:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
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4000-520-616
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Protocol Download
