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Abnova/ABCG2 monoclonal antibody, clone 3G8/1kit/MAB10478
  • Abnova/ABCG2 monoclonal antibody, clone 3G8/1kit/MAB10478

Abnova/ABCG2 monoclonal antibody, clone 3G8/1kit/MAB10478

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貨號(hào): MAB10478
品牌: Abnova
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  • 詳情
  • 使用說(shuō)明
  • 常見問(wèn)題
      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Mouse monoclonal antibody raised against partial recombinant ABCG2.
      • Immunogen:
      • Recombinant protein corresponding to human ABCG2.
      • Host:
      • Mouse
      • Theoretical MW (kDa):
      • 72
      • Reactivity:
      • Human, Monkey, Mouse
      • Form:
      • Liquid
      • Isotype:
      • IgG1
      • Recommend Usage:
      • ELISA (1:10000)Western Blot (1:500-1:2000)Immunohistochemistry (1:200-1:1000)Immunofluorescence (1:200-1:1000)Flow cytometry (1:200-1:400)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In ascites (0.03% sodium azide)
      • Storage Instruction:
      • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • Western blot analysis using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) against NIH/3T3 (1) and COS-7 (2) cell lysate.
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues (A) and skeletal muscle tissues (B) using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) with DAB staining.
      • Immunofluorescence
      • Immunofluorescence
      • Immunofluorescence analysis of HeLa cells using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
      • Enzyme-linked Immunoabsorbent Assay
      • Enzyme-linked Immunoabsorbent Assay
      • ELISA detection with ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478).
      • Flow Cytometry
      • Flow Cytometry
      • Flow cytometric analysis of HepG2 cells using ABCG2 monoclonal antibody, clone 3G8 (Cat # MAB10478) (green) and negative control (purple).
      • Application Image
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • enlarge
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • enlarge
      • Immunofluorescence
      • Immunofluorescence
      • enlarge
      • Enzyme-linked Immunoabsorbent Assay
      • Enzyme-linked Immunoabsorbent Assay
      • enlarge
      • Flow Cytometry
      • Flow Cytometry
      • enlarge
      • Gene Information
      • Entrez GeneID:
      • 9429
      • Gene Name:
      • ABCG2
      • Gene Alias:
      • ABC15,ABCP,BCRP,BCRP1,BMDP,CD338,CDw338,EST157481,MGC102821,MRX,MXR,MXR1
      • Gene Description:
      • ATP-binding cassette, sub-family G (WHITE), member 2
      • Omim ID:
      • 603756
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
      • Other Designations:
      • ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
      • Gene Pathway
      • ABC transporters
      • Related Disease
      • Adenocarcinoma
      • Alzheimer Disease
      • Alzheimer disease
      • Atherosclerosis
      • Atherosclerosis
      • Brain Ischemia
      • Brain Neoplasms
      • Breast cancer
      • Carcinoma, Non-Small-Cell Lung
      • Carcinoma, Renal Cell
      • Carcinoma, Squamous Cell
      • Cardiovascular Diseases
      • Colon cancer
      • Colorectal Neoplasms
      • Coronary Artery Disease
      • Coronary Disease
      • Crohn"s disease
      • Diabetes Complications
      • Diabetes Mellitus, Type 2
          • ... see more
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