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Abnova/CD244 polyclonal antibody/1kit/PAB19379
  • Abnova/CD244 polyclonal antibody/1kit/PAB19379

Abnova/CD244 polyclonal antibody/1kit/PAB19379

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貨號: PAB19379
品牌: Abnova
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  • 詳情
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      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
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      • Specification
      • Product Description:
      • Rabbit polyclonal antibody raised against synthetic peptide of CD244.
      • Immunogen:
      • A synthetic peptide corresponding to 16 amino acids near C-terminus of human CD244.
      • Sequence:
      • PKAQNPARLSRKELEN
      • Host:
      • Rabbit
      • Reactivity:
      • Human, Mouse, Rat
      • Specificity:
      • At least three isoforms of CD244 are known to exist. This antibody is predicted to not cross-react with other SLAM protein family members.
      • Form:
      • Liquid
      • Purification:
      • Peptide affinity purification
      • Concentration:
      • 1 mg/mL
      • Recommend Usage:
      • Western Blot (1-2 ug/mL)Immunofluorescence (20 ug/mL)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (0.02% sodium azide)
      • Storage Instruction:
      • Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • Western blot analysis of CD244 in Daudi cell lysate with CD244 polyclonal antibody (Cat # PAB19379) at (1) 1 and (2) 2 ug/mL.
      • Immunofluorescence
      • Immunofluorescence
      • Immunofluorescencent staining of Daudi cells with CD244 polyclonal antibody (Cat # PAB19379) at 20 ug/mL.
      • Enzyme-linked Immunoabsorbent Assay
      • Application Image
      • Western Blot (Cell lysate)
      • Western Blot (Cell lysate)
      • enlarge
      • Immunofluorescence
      • Immunofluorescence
      • enlarge
      • Enzyme-linked Immunoabsorbent Assay
      • Gene Information
      • Entrez GeneID:
      • 51744
      • Protein Accession#:
      • NP_1160135
      • Gene Name:
      • CD244
      • Gene Alias:
      • 2B4,NAIL,NKR2B4,Nmrk,SLAMF4
      • Gene Description:
      • CD244 molecule, natural killer cell receptor 2B4
      • Omim ID:
      • 605554
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Natural killer (NK) cells express both activating and inhibitory cell surface receptors. Inhibitory signaling receptors all possess cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, or ITIMs, whereas the activating receptors lack ITIMs and associate with DAP12 (TYROBP; MIM 604142), which contains an immunoreceptor tyrosine-based activation motif, or ITAM. Killer cell immunoglobulin (Ig)-like receptors, or KIRs (see KIR2DL1; MIM 604936), and other NK cell receptors interact with major histocompatibility complex (MHC) molecules (see MIM 142800). Members of the CD2 (MIM 186990) family adhere to each other instead. The cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function (Boles et al., 1999 [PubMed 10458320]).[supplied by OMIM
      • Other Designations:
      • CD244 natural killer cell receptor 2B4,NK cell activation inducing ligand NAIL,OTTHUMP00000027884,natural killer cell receptor 2B4
      • Gene Pathway
      • Natural killer cell mediated cytotoxicity
      • Related Disease
      • Arthritis, Rheumatoid
      • Cell Transformation, Neoplastic
      • Genetic Predisposition to Disease
      • Lupus Erythematosus, Systemic
      • Tobacco Use Disorder
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