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Abnova/ACPP polyclonal antibody/1kit/PAB2990
  • Abnova/ACPP polyclonal antibody/1kit/PAB2990

Abnova/ACPP polyclonal antibody/1kit/PAB2990

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貨號: PAB2990
品牌: Abnova
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      • Specification
      • Gene Info
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • Rabbit polyclonal antibody raised against synthetic peptide of ACPP.
      • Immunogen:
      • A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ACPP.
      • Host:
      • Rabbit
      • Reactivity:
      • Human
      • Form:
      • Liquid
      • Purification:
      • Ammonium sulfate precipitation
      • Recommend Usage:
      • Western Blot (1:1000)Immunohistochemistry (1:10-50)The optimal working dilution should be determined by the end user.
      • Storage Buffer:
      • In PBS (0.09% sodium azide)
      • Storage Instruction:
      • Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
      • Datasheet:
      • PDF DownloadDownload
      • Publication Reference
      • 1.
      • Prostatic acid phosphatase is not a prostate specific target.Quintero IB, Araujo CL, Pulkka AE, Wirkkala RS, Herrala AM, Eskelinen EL, Jokitalo E, Hellstrom PA, Tuominen HJ, Hirvikoski PP, Vihko PT.Cancer Res. 2007 Jul 15;67(14):6549-54.
      • 2.
      • Identification of HLA-DRB1*1501-restricted T-cell epitopes from human prostatic acid phosphatase.Klyushnenkova EN, Kouiavskaia DV, Kodak JA, Vandenbark AA, Alexander RB.Prostate. 2007 Jul 1;67(10):1019-28.
      • 3.
      • The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase.Johnson JL, Ellis BA, Noack D, Seabra MC, Catz SD.Biochem J. 2005 Nov 1;391(Pt 3):699-710.
      • Applications
      • Western Blot (Tissue lysate)
      • Western Blot (Tissue lysate)
      • Western blot analysis of ACPP polyclonal antibody (Cat # PAB2990) in mouse lung tissue lysates (35 ug/lane). ACPP (arrow) was detected using the purified polyclonal antibody.
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Formalin-fixed and paraffin-embedded human lung carcinomareacted with ACPP polyclonal antibody (Cat # PAB2990), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
      • Application Image
      • Western Blot (Tissue lysate)
      • Western Blot (Tissue lysate)
      • enlarge
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
      • enlarge
      • Gene Information
      • Entrez GeneID:
      • 55
      • Protein Accession#:
      • NP_001090;P15309
      • Gene Name:
      • ACPP
      • Gene Alias:
      • ACP-3,ACP3,PAP
      • Gene Description:
      • acid phosphatase, prostate
      • Omim ID:
      • 171790
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq
      • Other Designations:
      • prostatic acid phosphotase
      • Gene Pathway
      • gamma-Hexachlorocyclohexane degradation
      • Riboflavin metabolism
      • Related Disease
      • Tobacco Use Disorder
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